Mushrooms are highly nutritive, low-calorie food with good quality proteins, vitamins and minerals. Mushrooms are an important natural source of foods and medicines. Traditional aboriginals knew the medicinal importance of edible and wild mushrooms and these are now being screened for their bioactivity in various ailments. It represents a major and untapped source of potent new pharmaceutical products. A wide range of therapeutic activities including antitumor, hypocholesterolemic, hypoglycemic, cardiovascular, antimicrobial and antiviral are reported in mushrooms. In developing countries like India, mushroom progress is a boon in the field of food, medicine, and in generating employment. The alternative systems of medicine utilize the curative properties of mushrooms. The present review aimed to discuss on medicinal importance as nutraceuticals, antioxidatives, cardiovascular, hypercholesterolemia, antimicrobial, hepatoprotective and anticancer availability of mushroom medicines as well as the application of biotechnology in the mushroom cultivation in order to optimize the utilization.
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